Cargando...
E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFα-induced JNK activation
The zinc finger transcription factor Miz1 is a negative regulator of TNFα-induced JNK activation and cell death through inhibition of TRAF2 K63-polyubiquitination in a transcription-independent manner. Upon TNFα stimulation, Miz1 undergoes K48-linked polyubiquitination and proteasomal degradation, t...
Gardado en:
| Main Authors: | , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2010
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922175/ https://ncbi.nlm.nih.gov/pubmed/20624960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913690107 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|