Φορτώνει......
Fourier analysis and systems identification of the p53 feedback loop
A key circuit in the response of cells to damage is the p53–mdm2 feedback loop. This circuit shows sustained, noisy oscillations in individual human cells following DNA breaks. Here, we apply an engineering approach known as systems identification to quantify the in vivo interactions in the circuit...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922141/ https://ncbi.nlm.nih.gov/pubmed/20622152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001107107 |
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