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Oscillations and variability in the p53 system

Understanding the dynamics and variability of protein circuitry requires accurate measurements in living cells as well as theoretical models. To address this, we employed one of the best-studied protein circuits in human cells, the negative feedback loop between the tumor suppressor p53 and the onco...

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Détails bibliographiques
Auteurs principaux: Geva-Zatorsky, Naama, Rosenfeld, Nitzan, Itzkovitz, Shalev, Milo, Ron, Sigal, Alex, Dekel, Erez, Yarnitzky, Talia, Liron, Yuvalal, Polak, Paz, Lahav, Galit, Alon, Uri
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681500/
https://ncbi.nlm.nih.gov/pubmed/16773083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100068
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