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Calcium-dependent Regulation of Protein Kinase D Revealed by a Genetically Encoded Kinase Activity Reporter

Protein kinase D (PKD) regulates many diverse cellular functions in response to diacylglycerol. To monitor PKD signaling in live cells, we generated a genetically encoded fluorescent reporter for PKD activity, DKAR (D kinase activity reporter). DKAR expressed in mammalian cells undergoes reversible...

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Bibliografski detalji
Glavni autori: Kunkel, Maya T., Toker, Alex, Tsien, Roger Y., Newton, Alexandra C.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921767/
https://ncbi.nlm.nih.gov/pubmed/17189263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M608086200
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