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Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-α and macrophage migration inhibitory factor concentrations in African children

BACKGROUND: Iron deficiency and the Q248H mutation in the gene, SLC40A1, that encodes for the cellular iron exporter, ferroportin, are both common in African children. The iron status of macrophages influences the pro-inflammatory response of these cells. We hypothesized that Q248H mutation may modi...

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Bibliografski detalji
Glavni autori: Kasvosve, Ishmael, Debebe, Zufan, Nekhai, Sergei, Gordeuk, Victor R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921676/
https://ncbi.nlm.nih.gov/pubmed/20460119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2010.04.031
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