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Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin
Ferroportin Q248H mutation has an allele frequency of 2.2–13.4% in African populations and is associated with a mild tendency to increased serum ferritin in the general population. Some investigators have reported that ferroportin Q248H is degraded after exposure to hepcidin in exactly the same mann...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Ferrata Storti Foundation
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3659936/ https://ncbi.nlm.nih.gov/pubmed/23065513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.066530 |
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