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Hepcidin induces HIV-1 transcription inhibited by ferroportin

BACKGROUND: Physiological regulation of cellular iron involves iron export by the membrane protein, ferroportin, the expression of which is induced by iron and negatively modulated by hepcidin. We previously showed that iron chelation is associated with decreased HIV-1 transcription. We hypothesized...

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Detalhes bibliográficos
Main Authors: Xu, Min, Kashanchi, Fatah, Foster, Altreisha, Rotimi, Jamie, Turner, Willie, Gordeuk, Victor R, Nekhai, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022686/
https://ncbi.nlm.nih.gov/pubmed/21126372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-104
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