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Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora
Polo-like kinase 1 (Plk1) and Aurora A play key roles in centrosome maturation, spindle assembly, and chromosome segregation during cell division. Here we show that the functions of these kinases during early mitosis are coordinated through Bora, a partner of Aurora A first identified in Drosophila....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921497/ https://ncbi.nlm.nih.gov/pubmed/18521620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-008-0165-5 |
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