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Chemomechanical Regulation of SNARE Proteins Studied with Molecular Dynamics Simulations
SNAP-25B is a neuronal protein required for neurotransmitter (NT) release and is the target of Botulinum Toxins A and E. It has two SNARE domains that form a four-helix bundle when combined with syntaxin 1A and synaptobrevin. Formation of the three-protein complex requires both SNARE domains of SNAP...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920728/ https://ncbi.nlm.nih.gov/pubmed/20713006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.019 |
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