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Union of Geometric Constraint-Based Simulations with Molecular Dynamics for Protein Structure Prediction

Although proteins are a fundamental unit in biology, the mechanism by which proteins fold into their native state is not well understood. In this work, we explore the assembly of secondary structure units via geometric constraint-based simulations and the effect of refinement of assembled structures...

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Bibliographic Details
Main Authors: Glembo, Tyler J., Ozkan, S. Banu
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849074/
https://ncbi.nlm.nih.gov/pubmed/20303862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.031
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