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‘A mover and a shaker’: 53BP1 allows DNA doublestrand breaks a chance to dance and unite

The DNA damage response mediator protein, p53-binding protein 1 (53BP1), is dispensable for the repair of most DNA doublestrand breaks (DSBs) induced by ionising radiation. However, two recent studies have shown that 53BP1 is required for rejoining of distant DSB ends and that it promotes the moveme...

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Bibliografiske detaljer
Main Authors: Goodarzi, Aaron A, Jeggo, Penny A
Format: Artigo
Sprog:Inglês
Udgivet: Biology Reports Ltd 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920668/
https://ncbi.nlm.nih.gov/pubmed/20948664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-21
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