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‘A mover and a shaker’: 53BP1 allows DNA doublestrand breaks a chance to dance and unite
The DNA damage response mediator protein, p53-binding protein 1 (53BP1), is dispensable for the repair of most DNA doublestrand breaks (DSBs) induced by ionising radiation. However, two recent studies have shown that 53BP1 is required for rejoining of distant DSB ends and that it promotes the moveme...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biology Reports Ltd
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920668/ https://ncbi.nlm.nih.gov/pubmed/20948664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-21 |
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