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Agmatine reduces extracellular glutamate during pentylenetetrazole-induced seizures in rat brain: A potential mechanism for the anticonvulsive effects

Glutamate has been implicated in the initiation and spread of seizure activity. Agmatine, an endogenous neuromodulator, is an antagonist of NMDA receptors and has anticonvulsive effects. Whether agmatine regulate glutamate release, as measured by in vivo microdialysis, is not known. In this study, w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Feng, Yangzheng, LeBlanc, Michael H., Regunathan, Soundar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920494/
https://ncbi.nlm.nih.gov/pubmed/16125317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2005.08.008
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