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Agmatine: Biological role and therapeutic potentials in morphine analgesia and dependence

Agmatine is an amine that is formed by decarboxylation of L-arginine by the enzyme arginine decarboxylase (ADC) and hydrolyzed by the enzyme agmatinase to putrescine. Agmatine binds to several target receptors in the brain and has been proposed as a novel neuromodulator. In animal studies, agmatine...

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Библиографические подробности
Главный автор: Regunathan, Soundar
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761054/
https://ncbi.nlm.nih.gov/pubmed/17025265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080356
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