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Agmatine: Biological role and therapeutic potentials in morphine analgesia and dependence
Agmatine is an amine that is formed by decarboxylation of L-arginine by the enzyme arginine decarboxylase (ADC) and hydrolyzed by the enzyme agmatinase to putrescine. Agmatine binds to several target receptors in the brain and has been proposed as a novel neuromodulator. In animal studies, agmatine...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761054/ https://ncbi.nlm.nih.gov/pubmed/17025265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080356 |
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