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Nicotinamide reduces hypoxic ischemic brain injury in the newborn rat

Nicotinamide reduces ischemic brain injury in adult rats. Can similar brain protection be seen in newborn animals? Seven-day-old rat pups had the right carotid artery permanently ligated followed by 2.5 h of 8% oxygen. Nicotinamide 250 or 500 mg/kg was administered i.p. 5 min after reoxygenation, wi...

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Detalhes bibliográficos
Main Authors: Feng, Yangzheng, Paul, Ian A., LeBlanc, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146056/
https://ncbi.nlm.nih.gov/pubmed/16533659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2005.11.011
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