Laboratory and Clinical Outcomes of Pharmacogenetic vs. Clinical Protocols for Warfarin Initiation in Orthopedic Patients

BACKGROUND: Warfarin is commonly prescribed for prophylaxis and treatment of thromboembolism after orthopedic surgery. During warfarin initiation, out-of-range International Normalized Ratio (INR) values and adverse events are common. METHODS: In orthopedic patients beginning warfarin therapy, we de...

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Hlavní autoři: Lenzini, Petra A., Grice, Gloria R., Milligan, Paul E., Dowd, Mary Beth, Subherwal, Sumeet, Deych, Elena, Eby, Charles S., King, Cristi R., Porche-Sorbet, Rhonda M., Murphy, Claire V., Marchand, Renee, Millican, Eric A., Barrack, Robert L., Clohisy, John C., Kronquist, Kathryn, Gatchel, Susan K., Gage, Brian F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920450/
https://ncbi.nlm.nih.gov/pubmed/18662264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2008.03095.x
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