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Warfarin Pharmacogenetics: does more accurate dosing benefit patients?
After a decade of clinical investigation, pharmacogenetic guided initial dosing of warfarin is at a crossroads. Genotypes for two single nucleotide polymorphisms (SNP) in cytochrome P 450 2C9 gene , affecting warfarin metabolism, and one SNP in Vitamin K reductase complex 1 gene, affecting warfarin...
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Publicado no: | Semin Thromb Hemost |
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Autor principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407810/ https://ncbi.nlm.nih.gov/pubmed/23047421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1326789 |
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