Pre-operative CTLA-4 blockade: tolerability and immune monitoring in the setting of a pre-surgical clinical trial

PURPOSE: CTLA-4 blockade is being explored in numerous clinical trials as an immune based therapy for different malignancies. Our group conducted the first pre-operative clinical trial with the anti-CTLA-4 antibody ipilimumab in 12 patients with localized urothelial carcinoma of the bladder. EXPERIM...

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Main Authors: Carthon, Bradley, Wolchok, Jedd D., Yuan, Jianda, Kamat, Ashish, Ng Tang, Derek S., Sun, Jingjing, Ku, Geoffrey, Troncoso, Patricia, Logothetis, Christopher J., Allison, James P., Sharma, Padmanee
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919850/
https://ncbi.nlm.nih.gov/pubmed/20460488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0569
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