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Numerical modelling of microRNA-mediated mRNA decay identifies novel mechanism of microRNA controlled mRNA downregulation

Post-transcriptional control of mRNA by micro-RNAs (miRNAs) represents an important mechanism of gene regulation. miRNAs act by binding to the 3′ untranslated region (3′UTR) of an mRNA, affecting the stability and translation of the target mRNA. Here, we present a numerical model of miRNA-mediated m...

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Bibliographische Detailangaben
Hauptverfasser: Vohradsky, Jiri, Panek, Josef, Vomastek, Tomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919720/
https://ncbi.nlm.nih.gov/pubmed/20371515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq220
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