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Numerical modelling of microRNA-mediated mRNA decay identifies novel mechanism of microRNA controlled mRNA downregulation

Post-transcriptional control of mRNA by micro-RNAs (miRNAs) represents an important mechanism of gene regulation. miRNAs act by binding to the 3′ untranslated region (3′UTR) of an mRNA, affecting the stability and translation of the target mRNA. Here, we present a numerical model of miRNA-mediated m...

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Detalhes bibliográficos
Main Authors: Vohradsky, Jiri, Panek, Josef, Vomastek, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919720/
https://ncbi.nlm.nih.gov/pubmed/20371515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq220
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