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Numerical modelling of microRNA-mediated mRNA decay identifies novel mechanism of microRNA controlled mRNA downregulation

Post-transcriptional control of mRNA by micro-RNAs (miRNAs) represents an important mechanism of gene regulation. miRNAs act by binding to the 3′ untranslated region (3′UTR) of an mRNA, affecting the stability and translation of the target mRNA. Here, we present a numerical model of miRNA-mediated m...

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書誌詳細
主要な著者: Vohradsky, Jiri, Panek, Josef, Vomastek, Tomas
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919720/
https://ncbi.nlm.nih.gov/pubmed/20371515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq220
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