A Single Asparagine-Linked Glycosylation Site of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Facilitates Inhibition by Mannose-Binding Lectin through Multiple Mechanisms

Mannose-binding lectin (MBL) is a serum protein that plays an important role in host defenses as an opsonin and through activation of the complement system. The objective of this study was to assess the interactions between MBL and severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) g...

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Détails bibliographiques
Auteurs principaux: Zhou, Yanchen, Lu, Kai, Pfefferle, Susanne, Bertram, Stephanie, Glowacka, Ilona, Drosten, Christian, Pöhlmann, Stefan, Simmons, Graham
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919028/
https://ncbi.nlm.nih.gov/pubmed/20573835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00554-10
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