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Functional Properties of the Human Cytomegalovirus IE86 Protein Required for Transcriptional Regulation and Virus Replication

The human cytomegalovirus (HCMV) IE86 protein is essential for HCMV replication due to its ability to transactivate critical viral early promoters. In the current study, we performed a comprehensive mutational analysis between amino acids (aa) 535 and 545 of IE86 and assessed the impact of these mut...

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Autors principals: Harris, Siabhon M., Bullock, Brady, Westgard, Elizabeth, Zhu, Hua, Stenberg, Richard M., Kerry, Julie A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919014/
https://ncbi.nlm.nih.gov/pubmed/20554773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00327-10
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