Functional Properties of the Human Cytomegalovirus IE86 Protein Required for Transcriptional Regulation and Virus Replication

The human cytomegalovirus (HCMV) IE86 protein is essential for HCMV replication due to its ability to transactivate critical viral early promoters. In the current study, we performed a comprehensive mutational analysis between amino acids (aa) 535 and 545 of IE86 and assessed the impact of these mut...

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Detalhes bibliográficos
Main Authors: Harris, Siabhon M., Bullock, Brady, Westgard, Elizabeth, Zhu, Hua, Stenberg, Richard M., Kerry, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919014/
https://ncbi.nlm.nih.gov/pubmed/20554773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00327-10
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