Molecular model of SARS coronavirus polymerase: implications for biochemical functions and drug design

The causative agent of severe acute respiratory syndrome (SARS) is a previously unidentified coronavirus, SARS-CoV. The RNA-dependent RNA polymerase (RdRp) of SARS-CoV plays a pivotal role in viral replication and is a potential target for anti-SARS therapy. There is a lack of structural or biochemi...

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Hauptverfasser: Xu, Xiang, Liu, Yunqing, Weiss, Susan, Arnold, Eddy, Sarafianos, Stefan G., Ding, Jianping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC291860/
https://ncbi.nlm.nih.gov/pubmed/14654687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg916
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