Molecular Modeling and Biochemical Characterization Reveal the Mechanism of Hepatitis B Virus Polymerase Resistance to Lamivudine (3TC) and Emtricitabine (FTC)

Success in treating hepatitis B virus (HBV) infection with nucleoside analog drugs like lamivudine is limited by the emergence of drug-resistant viral strains upon prolonged therapy. The predominant lamivudine resistance mutations in HBV-infected patients are Met552IIe and Met552Val (Met552Ile/Val),...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Das, Kalyan, Xiong, Xiaofeng, Yang, Huiling, Westland, Christopher E., Gibbs, Craig S., Sarafianos, Stefan G., Arnold, Edward
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2001
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC114232/
https://ncbi.nlm.nih.gov/pubmed/11312349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.10.4771-4779.2001
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak