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Using DNA Methylation Patterns to Infer Tumor Ancestry

BACKGROUND: Exactly how human tumors grow is uncertain because serial observations are impractical. One approach to reconstruct the histories of individual human cancers is to analyze the current genomic variation between its cells. The greater the variations, on average, the greater the time since...

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Autors principals: Hong, You Jin, Marjoram, Paul, Shibata, Darryl, Siegmund, Kimberly D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918495/
https://ncbi.nlm.nih.gov/pubmed/20711251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012002
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