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Using DNA Methylation Patterns to Infer Tumor Ancestry

BACKGROUND: Exactly how human tumors grow is uncertain because serial observations are impractical. One approach to reconstruct the histories of individual human cancers is to analyze the current genomic variation between its cells. The greater the variations, on average, the greater the time since...

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Hlavní autoři: Hong, You Jin, Marjoram, Paul, Shibata, Darryl, Siegmund, Kimberly D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918495/
https://ncbi.nlm.nih.gov/pubmed/20711251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012002
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