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Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers
Cancers are clonal expansions, but how a single, transformed human cell grows into a billion-cell tumor is uncertain because serial observations are impractical. Potentially, this history is surreptitiously recorded within genomes that become increasingly numerous, polymorphic, and physically separa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651202/ https://ncbi.nlm.nih.gov/pubmed/19261858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810276106 |
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