Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase

Uroporphyrinogen decarboxylase (URO-D), an essential enzyme that functions in the heme biosynthetic pathway, catalyzes decarboxylation of all four acetate groups of uroporphyrinogen to form coproporphyrinogen. Here we report crystal structures of URO-D in complex with the I and III isomer coproporph...

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Argitaratua izan da:	EMBO J
Egile Nagusiak:	Phillips, John D., Whitby, Frank G., Kushner, James P., Hill, Christopher P.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Publishing Group 2003
Gaiak:	Articles
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291847/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14633982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg606
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