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Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Uroporphyrinogen decarboxylase (URO-D), an essential enzyme that functions in the heme biosynthetic pathway, catalyzes decarboxylation of all four acetate groups of uroporphyrinogen to form coproporphyrinogen. Here we report crystal structures of URO-D in complex with the I and III isomer coproporph...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291847/ https://ncbi.nlm.nih.gov/pubmed/14633982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg606 |
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