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Human uroporphyrinogen III synthase: molecular cloning, nucleotide sequence, and expression of a full-length cDNA.

Uroporphyrinogen III synthase [URO-synthase; hydroxymethylbilane hydro-lyase (cyclizing), EC 4.2.1.75], the fourth enzyme in the heme biosynthetic pathway, is responsible for conversion of the linear tetrapyrrole, hydroxymethylbilane, to the cyclic tetrapyrrole, uroporphyrinogen III. The deficient a...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tsai, S F, Bishop, D F, Desnick, R J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174619/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7049
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