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Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Uroporphyrinogen decarboxylase (URO-D), an essential enzyme that functions in the heme biosynthetic pathway, catalyzes decarboxylation of all four acetate groups of uroporphyrinogen to form coproporphyrinogen. Here we report crystal structures of URO-D in complex with the I and III isomer coproporph...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291847/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14633982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg606 |
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