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Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase

Uroporphyrinogen decarboxylase (URO-D), an essential enzyme that functions in the heme biosynthetic pathway, catalyzes decarboxylation of all four acetate groups of uroporphyrinogen to form coproporphyrinogen. Here we report crystal structures of URO-D in complex with the I and III isomer coproporph...

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書誌詳細
主要な著者: Phillips, John D., Whitby, Frank G., Kushner, James P., Hill, Christopher P.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC291847/
https://ncbi.nlm.nih.gov/pubmed/14633982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg606
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