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Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
The cytokines IL-1 and TNF induce expression of a series of genes that regulate inflammation through activation of NF-κB signal transduction pathways. TAK1, a MAPKKK, is critical for both IL-1- and TNF-induced activation of the NF-κB pathway. TAB2, a TAK1-binding protein, is involved in IL-1-induced...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291846/ https://ncbi.nlm.nih.gov/pubmed/14633987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg605 |
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