Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling
The cytokines IL-1 and TNF induce expression of a series of genes that regulate inflammation through activation of NF-κB signal transduction pathways. TAK1, a MAPKKK, is critical for both IL-1- and TNF-induced activation of the NF-κB pathway. TAB2, a TAK1-binding protein, is involved in IL-1-induced...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14633987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg605 |
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