PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protein that regulates hepatic low-density lipoprotein receptor (LDLR) levels in humans. PCSK9 has also been shown to regulate the levels of additional membrane-bound proteins in vitro, including the very low-density lipoprotein rec...

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Detalhes bibliográficos
Main Authors: Liu, Mali, Wu, Guoxin, Baysarowich, Jennifer, Kavana, Michael, Addona, George H., Bierilo, Kathleen K., Mudgett, John S., Pavlovic, Guillaume, Sitlani, Ayesha, Renger, John J., Hubbard, Brian K., Fisher, Timothy S., Zerbinatti, Celina V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918444/
https://ncbi.nlm.nih.gov/pubmed/20453200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M006635
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