Arkadia amplifies TGF-β superfamily signalling through degradation of Smad7

Arkadia was originally identified as a protein that enhances signalling activity of Nodal and induces mammalian nodes during early embryogenesis; however, the mechanisms by which Arkadia affects transforming growth factor-β (TGF-β) superfamily signalling have not been determined. Here we show that A...

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Hauptverfasser: Koinuma, Daizo, Shinozaki, Masahiko, Komuro, Akiyoshi, Goto, Kouichiro, Saitoh, Masao, Hanyu, Aki, Ebina, Masahito, Nukiwa, Toshihiro, Miyazawa, Keiji, Imamura, Takeshi, Miyazono, Kohei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC291827/
https://ncbi.nlm.nih.gov/pubmed/14657019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg632
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