A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression

Thyroid transcription factor-1 (TTF-1, also known as NKX2-1) is a tissue-specific transcription factor in lung epithelial cells. Although TTF-1 inhibits the epithelial-to-mesenchymal transition induced by transforming growth factor-β (TGF-β) in lung adenocarcinoma cells, the mechanism through which...

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Autors principals: Isogaya, Kazunobu, Koinuma, Daizo, Tsutsumi, Shuichi, Saito, Roy-Akira, Miyazawa, Keiji, Aburatani, Hiroyuki, Miyazono, Kohei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123303/
https://ncbi.nlm.nih.gov/pubmed/25060702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.97
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