RB1CC1 Protein Positively Regulates Transforming Growth Factor-β Signaling through the Modulation of Arkadia E3 Ubiquitin Ligase Activity

Transforming growth factor-β (TGF-β) signaling is controlled by a variety of regulators, of which Smad7, c-Ski, and SnoN play a pivotal role in its negative regulation. Arkadia is a RING-type E3 ubiquitin ligase that targets these negative regulators for degradation to enhance TGF-β signaling. In th...

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Detalhes bibliográficos
Main Authors: Koinuma, Daizo, Shinozaki, Masahiko, Nagano, Yoshiko, Ikushima, Hiroaki, Horiguchi, Kana, Goto, Kouichiro, Chano, Tokuhiro, Saitoh, Masao, Imamura, Takeshi, Miyazono, Kohei, Miyazawa, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173165/
https://ncbi.nlm.nih.gov/pubmed/21795712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.227561
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