RB1CC1 Activates RB1 Pathway and Inhibits Proliferation and Cologenic Survival in Human Cancer

RB1-inducible coiled-coil 1 (RB1CC1, also known as FIP200) plays a role in the enhancement of the RB1 pathway through the direct binding to a GC-rich region 201bp upstream (from the initiation ATG) of the RB1 promoter. Here, we identified hSNF5 and p53 as the binding partners of RB1CC1 by immunoprec...

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Main Authors: Chano, Tokuhiro, Ikebuchi, Kaichiro, Ochi, Yasuko, Tameno, Hitosuke, Tomita, Yasuhiko, Jin, Yufen, Inaji, Hideo, Ishitobi, Makoto, Teramoto, Koji, Nishimura, Ichiro, Minami, Kahori, Inoue, Hirokazu, Isono, Takahiro, Saitoh, Masao, Shimada, Taketoshi, Hisa, Yasuo, Okabe, Hidetoshi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894861/
https://ncbi.nlm.nih.gov/pubmed/20614030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011404
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