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Development and Validation of a UPLC Hydrogen/Deuterium Exchange Mass Spectrometry System
RP-81 Hydrogen/deuterium exchange mass spectrometry (HXMS) has proven to be a useful analytical method for the study of protein dynamics and changes to protein conformation. In order to maximize deuterium signal recovery during LC/MS analysis, rapid chromatographic separations at 0°C must be utilize...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association of Biomolecular Resource Facilities
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918096/ |
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