Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a

The anticancer agent 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) and its methyl ester (CDDO-Me) typically induce a broad spectrum of growth-inhibitory, proapoptotic, and antiangiogenic responses. Treatment of Panc1, Panc28, and L3.6pL pancreatic cancer cells with low micromolar concentratio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jutooru, Indira, Chadalapaka, Gayathri, Abdelrahim, Maen, Basha, Md Riyaz, Samudio, Ismael, Konopleva, Marina, Andreeff, Michael, Safe, Stephen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2010
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917860/
https://ncbi.nlm.nih.gov/pubmed/20488920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.064451
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