Divergent Signature motifs of Nucleotide Binding Domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and non interchangeable

Nucleotide Binding Domains (NBDs) of multidrug transporter of Candida albicans, CaCdr1p possess unique divergent amino acids in their conserved motifs. For example, NBD1 (N-terminal-NBD) possesses conserved Signature motifs while the same motif is divergent in NBD2 (C-terminal-NBD). In this study, w...

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Bibliographic Details
Main Authors: Kumar, Antresh, Shukla, Suneet, Mandal, Ajeet, Shukla, Sudhanshu, Ambudkar, Suresh V., Prasad, Rajendra
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917344/
https://ncbi.nlm.nih.gov/pubmed/20546701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.05.017
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