Reprogramming of peripheral blood cells to induced pluripotent stem cells

Direct reprogramming of human fibroblasts to induced pluripotent stem cells (iPS) has been achieved by ectopic expression of defined transcription factors. Derivation of human fibroblasts however is a time consuming process and requires punch biopsies or isolation of patient foreskin. Here we use a...

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Bibliographic Details
Main Authors: Staerk, Judith, Dawlaty, Meelad M, Gao, Qing, Maetzel, Dorothea, Hanna, Jacob, Sommer, Cesar A, Mostoslavsky, Gustavo, Jaenisch, Rudolf
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917234/
https://ncbi.nlm.nih.gov/pubmed/20621045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.06.002
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