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THE HER4 CYTOPLASMIC DOMAIN, BUT NOT ITS C-TERMINUS, INHIBITS MAMMARY CELL PROLIFERATION
Unlike the proliferative action of other EGF receptor family members, HER4/ErbB4 is often associated with growth inhibitory and differentiation signaling. These actions may involve HER4 two-step proteolytic processing by intra-membraneous γ-secretase, releasing the soluble, intracellular 80kDa HER4...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917064/ https://ncbi.nlm.nih.gov/pubmed/17505063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2006-0101 |
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