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THE HER4 CYTOPLASMIC DOMAIN, BUT NOT ITS C-TERMINUS, INHIBITS MAMMARY CELL PROLIFERATION
Unlike the proliferative action of other EGF receptor family members, HER4/ErbB4 is often associated with growth inhibitory and differentiation signaling. These actions may involve HER4 two-step proteolytic processing by intra-membraneous γ-secretase, releasing the soluble, intracellular 80kDa HER4...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917064/ https://ncbi.nlm.nih.gov/pubmed/17505063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2006-0101 |
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