The EGF receptor family--multiple roles in proliferation, differentiation, and neoplasia with an emphasis on HER4.

The EGF Receptor (EGFR), the first transmembrane receptor tyrosine kinase cloned and sequenced, and its closely related family members HER2, HER3, and HER4, play myriad roles in mammalian growth and development. Receptor activation involves ligand binding to separate receptors followed by formation...

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Bibliografiske detaljer
Main Authors: Earp, H. Shelton, Calvo, Benjamin F., Sartor, Carolyn I.
Format: Artigo
Sprog:Inglês
Udgivet: American Clinical and Climatological Association 2003
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194503/
https://ncbi.nlm.nih.gov/pubmed/12813928
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