HER4 Mediates Ligand-Dependent Antiproliferative and Differentiation Responses in Human Breast Cancer Cells

The function of the epidermal growth factor receptor (EGFR) family member HER4 remains unclear because its activating ligand, heregulin, results in either proliferation or differentiation. This variable response may stem from the range of signals generated by HER4 homodimers versus heterodimeric com...

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Autores principales: Sartor, Carolyn I., Zhou, Hong, Kozlowska, Ewa, Guttridge, Katherine, Kawata, Evelyn, Caskey, Laura, Harrelson, Jennifer, Hynes, Nancy, Ethier, Stephen, Calvo, Benjamin, Earp, H. Shelton
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC87087/
https://ncbi.nlm.nih.gov/pubmed/11390655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.13.4265-4275.2001
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