Protection of rhesus macaques from vaginal infection by vaginally delivered Maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor

An effective vaginal microbicide could reduce human immunodeficiency virus type 1 (HIV-1) transmission to women. Among microbicide candidates in clinical development is Maraviroc (MVC), a small molecule drug that binds the CCR5 co-receptor and impedes HIV-1 entry into cells. Delivered systemically,...

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Detaylı Bibliyografya
Asıl Yazarlar: Veazey, Ronald S., Ketas, Thomas J., Dufour, Jason, Moroney-Rasmussen, Terri, Green, Linda C., Klasse, P.J., Moore, John P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916941/
https://ncbi.nlm.nih.gov/pubmed/20629537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/655661
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