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Simian immunodeficiency virus selectively infects proliferating CD4(+) T cells in neonatal rhesus macaques

Infants infected with HIV have a more severe course of disease and persistently higher viral loads than HIV-infected adults. However, the underlying pathogenesis of this exacerbation remains obscure. Here we compared the rate of CD4(+) and CD8(+) T-cell proliferation in intestinal and systemic lymph...

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Detalhes bibliográficos
Main Authors: Wang, Xiaolei, Xu, Huanbin, Pahar, Bapi, Alvarez, Xavier, Green, Linda C., Dufour, Jason, Moroney-Rasmussen, Terri, Lackner, Andrew A., Veazey, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993622/
https://ncbi.nlm.nih.gov/pubmed/20716768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-273482
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