Genetic epistasis of IL23/IL17 pathway genes in Crohn’s disease

The IL23/IL17 pathway is pivotal in the development of chronic mucosal inflammation seen in Crohn’s disease (CD). Genetic variants in the IL23R and IL12B have been associated with CD susceptibility. We investigated ten genes within the IL23/IL17 pathway in a case-control study of 763 CD cases and 25...

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Main Authors: McGovern, Dermot P.B., Rotter, Jerome I., Mei, Ling, Haritunians, Talin, Landers, Carol, Derkowski, Carrie, Dutridge, Deb, Dubinsky, Marla, Ippoliti, Andy, Vasiliauskas, Eric, Mengesha, Emebet, King, Lily, Pressman, Sheila, Targan, Stephan R., Taylor, Kent D.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916929/
https://ncbi.nlm.nih.gov/pubmed/19235914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20855
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